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The results demonstrated a large level of apoptosis occurred following PQQ treatment, and the proportion of cell apoptosis was comparable to that of the cytotoxic cell death rate, indicating that PQQ may mainly induce apoptosis to kill chondrosarcoma cells

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To estimate the effect of the P72R variant on inflammatory signalling, we overexpressed the P72 or R72 variant of TP53 in p53 KO C3H10T1/2 adipocytes, before challenging the cells with 24 h of starvation (Supplementary Fig